Fishes have a two-chambered heart and a single circuit of blood flow.

Blood is pumped from the ventricle to the gills via arteries (blood vessels that carry blood away from the heart).

After picking up O[2] and expelling CO[2], blood returns to the atrium via veins (blood vessels that carry blood to the heart).

There is no segregation of oxygen-rich and oxygen-poor blood in the heart.