Induced fit between an enzyme and its substrate.
<P>
<lI> The  active site of this enzyme (hexokinase) forms a groove on its
surface.
<lI> When  the  substrate (glucose) binds the active site, it induces a
change in the protein's shape (conformation).
<P>
   This change allows more weak bonds to form, causing the active site to
   embrace the substrate and hold it in place.